
Jordyn Jeffrey
Clinic Founder & Head BHSc Naturopath
(Complex Thyroid & Hormone)
25/2/26, 10:00 pm
Hashimoto’s — deeper dive into the root-cause layers
The Root Causes of Hashimoto’s
Did you know that 90–95% of hypothyroidism is autoimmune (Hashimoto’s)? This means the immune system is mistakenly attacking thyroid tissue. While medication has its place, true healing requires looking at why this immune confusion is happening in the first place.
Hashimoto’s is rarely caused by one single factor; it is usually a combination of overlapping layers.
Common Root Cause Layers
1. Immune dysregulation
Triggers: Genetics, chronic stress, infections, toxins → immune confusion
Impact: Leads to TPO/Tg antibodies against thyroid tissue
Support with: vitamin D, selenium, zinc, stress reduction, immune-modulating herbs
2. Gut dysfunction
Triggers: Leaky gut, SIBO, candida, dysbiosis → antigens cross gut wall → immune attack
Testing: Test with stool analysis, SIBO breath test
Support with: gut-healing nutrients (glutamine, zinc carnosine), targeted antimicrobials, probiotics
3. Nutrient deficiencies
Common: selenium, zinc, iron, vitamin D, B12, iodine (sometimes)
Impact: Deficiency = poor T4→T3 conversion, increased oxidative stress
Action: Correct with diet + targeted supplements after testing
4. Hormonal imbalances
Triggers: Oestrogen dominance, PCOS, low progesterone, adrenal dysregulation
Impact: Cortisol imbalance suppresses thyroid conversion
Action: Address with blood sugar support, stress regulation, cycle support
5. Toxin exposure
Triggers: Fluoride, plastics, pesticides, mould, heavy metals → disrupt thyroid enzymes & hormones
Action: Reduce exposures (filtered water, clean products, mould testing if needed)
Support: Support detox pathways with protein, cruciferous veggies, antioxidants
6. Nervous system dysregulation
Triggers: Chronic stress/trauma → sympathetic dominance → reduced vagal tone
Impact: Leads to poor digestion + higher inflammation
Support with: meditation, vagal-stimulating practices, calming herbs (lemon balm, chamomile)
7. Dietary stress
Triggers: Under-eating, low-carb, fasting → cortisol spikes, low T3
Impact: Leads to fatigue, slowed metabolism, and hormone imbalances
Action: Rebuild with regular, balanced meals rich in protein & wholefood carbs
Every thyroid case is unique — it’s never just one of these. True healing = peeling back your unique root-cause layers and having a guided, personalised plan.